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Is Vacuum Assisted Closure a valid technique for debriding chronic leg ulcers?

S Lorée1, A Dompmartin, K Penven

  • 1Department of Dermatology, University Hospital, Caen, France.

Journal of Wound Care
|June 25, 2004
PubMed
Summary

Topical negative pressure therapy, known as Vacuum Assisted Closure (VAC), effectively reduced fibrinous tissue in chronic leg ulcers. This method promoted healing and the development of healthy new tissue.

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Area of Science:

  • Wound healing research
  • Biomedical engineering
  • Dermatology

Background:

  • Chronic leg ulcers present a significant clinical challenge.
  • Fibrinous exudate can impede wound healing.
  • Conventional treatments often yield suboptimal results for non-responsive ulcers.

Purpose of the Study:

  • To evaluate the efficacy of topical negative pressure therapy.
  • To assess the debridement of fibrinous tissue in chronic leg ulcers.
  • To determine the impact of Vacuum Assisted Closure (VAC) on wound healing.

Main Methods:

  • A prospective, open, non-comparative study was conducted.
  • Fifteen chronic leg ulcers unresponsive to other treatments were enrolled.
  • The Vacuum Assisted Closure (VAC) system was applied for six days.

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Main Results:

  • Median reduction in fibrinous tissue was 28% by day three and 40% by day six.
  • Significant fibrin reduction was observed in most patients within the first three days.
  • Continued reduction or stabilization of fibrin levels occurred between days three and six.

Conclusions:

  • Vacuum Assisted Closure (VAC) therapy demonstrated rapid efficacy in debriding fibrinous tissue.
  • The treatment promoted angiogenesis, leading to healthy tissue formation.
  • VAC therapy is a promising approach for managing complex chronic leg ulcers.