Related Experiment Video
Updated: Oct 7, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Assessment of the spatial occurrence of childhood leukaemia mortality using standardized rate ratios with a simple
M Aickin1, C A Chapin, T J Flood
1Department of Family and Community Medicine, University of Arizona, Tucson.
Abstract:
Reports of a suspected cluster of childhood leukaemia cases in West Central Phoenix have led to a number of epidemiological studies in the geographical area. We report here on a death certificate-based mortality study, which indicated an elevated rate ratio of 1.95 during 1966-1986, using the remainder of the Phoenix standard metropolitan statistical area (SMSA) as a comparison region. In the process of analysing the data from this study, a methodology for dealing with denominator variability in a standardized mortality ratio was developed using a simple linear Poisson model. This new approach is seen as being of general use in the analysis of standardized rate ratios (SRR), as well as being particularly appropriate for cluster investigations.
Related Concept Videos
Relative Risk
Odds Ratio
Statistical Methods for Analyzing Epidemiological Data
Comparing the Survival Analysis of Two or More Groups
The Mantel-Cox Log-Rank Test
Hazard Rate

