The unexpected consequences of a noisy environment
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Updated: Aug 23, 2026

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
1Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 424, Baltimore, MD 21205, USA. xwang@bme.jhu.edu
Abstract:
A recent study found that the functional organization of auditory cortex was disrupted when rats were exposed to a moderate level of continuous noise during early development. However, this detrimental effect on auditory cortex could be remedied later by stimulating the noise-reared rats with structured sounds. These findings suggest that the endpoint of the "critical period" could be extended well into adult life, which has significant implications for our understanding of cortical plasticity.
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