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MacroPore resorbable devices in craniofacial surgery.

Ralph E Holmes1, Steven R Cohen, G Bryan Cornwall

  • 1Craniofacial Surgery Service, Children's Hospital of San Diego, 8010 Frost Street, #412, San Diego, CA 92123, USA. rholmes@sdfaces.com

Clinics in Plastic Surgery
|June 29, 2004
PubMed
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Resorbable implants made from polylactide (PLa) and polyglycolide (PGa) polymers offer a safe and effective option for craniofacial reconstruction. These advanced biomaterials are successfully used in various surgical applications for treating craniofacial deformities.

Area of Science:

  • Biomaterials Science
  • Craniofacial Surgery
  • Polymer Science

Background:

  • Resorbable polymer implants are increasingly utilized for craniofacial deformities.
  • Polylactide (PLa) and polyglycolide (PGa) polymers exhibit a strong safety profile.
  • These polymers are approved for diverse craniofacial surgical applications.

Purpose of the Study:

  • To discuss the biomaterial properties of PLa and PGa implants.
  • To provide an overview of their application in craniofacial surgery.
  • To present clinical experience with specific resorbable implants.

Main Methods:

  • Review of biomaterial properties of PLa and PGa.
  • Overview of clinical applications in craniofacial surgery.
  • Presentation of clinical case series using MacroPore PLDLa and FRP implants.

Related Experiment Videos

Main Results:

  • PLa and PGa demonstrate excellent safety profiles across multiple study types.
  • These polymers are suitable for a wide range of craniofacial procedures.
  • Successful application in Le Fort osteotomies, distraction osteogenesis, and craniosynostosis repair.

Conclusions:

  • Resorbable PLa and PGa polymers are valuable tools in craniofacial surgery.
  • Clinical outcomes support the use of these implants for complex reconstructions.
  • Ongoing clinical series demonstrate efficacy in diverse craniofacial applications.