Related Experiment Video
Updated: Aug 23, 2026
Motion-Acuity Test for Visual Field Acuity Measurement with Motion-Defined Shapes
Published on: February 23, 2024
Automated quantitative assessment of wall motion in patients with poor acoustic windows
Jeanne M Decara1, Victor Mor-Avi, Lynn Weinert
1Noninvasive Cardiac Imaging Laboratory, University of Chicago, IL 60637, USA. jdecara@medicine.bsd.uchicago.edu
Background:
No technique exists for objective evaluation of left ventricular wall motion in contrast-enhanced images. We tested a new technique for quantification of regional fractional area change using contrast-enhanced power modulation imaging with color kinesis.
Methods:
The feasibility of this technique for detecting acute ischemia was first tested in 11 pigs. Next, the accuracy for detecting resting wall-motion abnormalities was determined in 52 patients requiring contrast and compared with conventional interpretation of 2-dimensional images by inexperienced readers. Expert interpretation of 2-dimensional images served as the gold standard.
Results:
In pigs, coronary occlusion resulted in reversible hypokinesis and reduced regional fractional area change. In patients with poor acoustic windows, this technique's accuracy for quantitative detection of resting wall-motion abnormalities was 86% compared with 81% for conventional interpretation by inexperienced readers (P <.01).
Conclusions:
Regional wall motion can be accurately assessed using color-encoded power modulation imaging for patients requiring contrast. This technique may prove a useful diagnostic aid to echocardiographers of varying levels of experience.
