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Two new quinoline glycoalkaloids from Echinops gmelinii
Yan-Fang Su1, Yang Luo, Cheng-Yun Guo
1College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin 300072, China. yfsuphd@yahoo.com
Journal of Asian Natural Products Research
|July 1, 2004
Abstract:
Two new glycosidic quinoline alkaloids, 1-methyl-4-methoxy-8-(beta-D-glucopyranosyloxy)-2(1H)-quinolinone (1) and 4-methoxy-8-(beta-D-glucopyranosyloxy)-2(1H)-quinolinone (2), have been isolated from the 1-butanol extract of the aerial parts of Echinops gmelinii (Compositae). Structural elucidation of the two new glycoalkaloids was based on their 1H, 13C, DEPT, HSQC, COSY, HMBC NMR spectra and high-resolution FAB-MS data. These two compounds are rare examples of quinoline alkaloidal glycosides from natural sources.