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Related Experiment Videos

Positive angle kappa in albinism.

Kimberly S Merrill1, Jane D Lavoie, Richard A King

  • 1Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|July 1, 2004
PubMed
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A positive angle kappa is nearly universal in albinism patients. This finding significantly impacts the measurement of eye alignment, potentially affecting surgical planning for strabismus.

Area of Science:

  • Ophthalmology
  • Genetics
  • Pediatric Medicine

Background:

  • Albinism is an inherited disorder characterized by reduced melanin production.
  • Strabismus (eye misalignment) is frequently observed in individuals with albinism.

Purpose of the Study:

  • To determine the prevalence of a positive angle kappa in patients with albinism.
  • To assess the influence of a positive angle kappa on the evaluation of binocular alignment.

Main Methods:

  • Retrospective chart review of 207 patients diagnosed with albinism.
  • Recorded angle kappa and eye alignment using prism and alternate-cover test (PACT) and Krimsky measurements.

Main Results:

  • A positive angle kappa was present in 99.6% of patients with albinism.

Related Experiment Videos

  • Krimsky measurements showed a mean difference of 17.11 prism diopters compared to PACT.
  • Positive angle kappa caused esodeviations to appear smaller and exodeviations to appear larger.

    • Conclusions:

    • A positive angle kappa is a common clinical feature in albinism.
    • The effect of positive angle kappa on alignment measurements (Krimsky) should be considered during surgical planning for extraocular muscles.
    • This is especially important when preoperative testing indicates binocular vision potential.