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Updated: Aug 23, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Silent myocardial infarction complicated by asymptomatic ventricular septal defect and deferred rupture of left
1The Department of Cardiothoracic Surgery, John Radcliffe Hospital, Headington, Oxford, England.
Insights
A silent myocardial infarction led to an undiagnosed ventricular septal defect. A second cardiac event revealed a pseudoaneurysm, successfully treated with surgery for both conditions.
Area of Science:
- Cardiology
- Cardiovascular Surgery
Background:
- Postinfarction ventricular septal defects (VSD) and left ventricular pseudoaneurysms (LVPSA) typically present with acute, severe symptoms.
- Silent myocardial infarction (MI) can lead to delayed and asymptomatic cardiac complications.
Purpose of the Study:
- To report a rare case of a patient with a silent MI, developing an asymptomatic VSD, followed by a second MI with LVPSA and exsanguination.
- To highlight the diagnostic challenges and successful surgical management of combined postinfarction VSD and LVPSA.
Main Methods:
- Case report of a 59-year-old male patient.
- Diagnostic workup included electrocardiogram (ECG), echocardiography, left ventriculography, and coronary angiography.
- Surgical intervention involved aneurysm resection, VSD repair, and coronary artery bypass grafting (CABG).
Main Results:
- The patient presented with symptoms after a second cardiac event, revealing an old anterior MI, a VSD, and a large, exsanguinating anterior LVPSA.
- Severe two-vessel coronary artery disease was identified.
- Successful surgical repair of the VSD and LVPSA, along with CABG, resulted in good recovery.
Conclusions:
- Combined postinfarction VSD and LVPSA can occur after a silent MI and present atypically.
- Prompt diagnosis and surgical intervention are crucial for favorable outcomes in such complex cases.
- This case underscores the importance of comprehensive cardiac evaluation even in the absence of initial overt symptoms.
Abstract:
Patients with a postinfarction ventricular septal defect or ruptured left ventricular pseudoaneurysm usually present with sudden cardiogenic shock or cardiac tamponade, respectively. We report the case of a 59-year-old man who had a silent myocardial infarction followed by an asymptomatic ventricular septal defect, both of which remained undiagnosed until the patient experienced a 2nd myocardial event 1 month later. This 2nd event was possibly a new infarction accompanied by left ventricular pseudoaneurysmal development and exsanguination, but not by tamponade. On admission, an electrocardiogram showed changes suggesting the presence of an old anterior myocardial infarction. Echocardiography revealed a ventricular septal defect and moderate pericardial perfusion, while left ventriculography disclosed a large extraventricular sac protruding from the anterior wall. The patient also had severe 2-vessel coronary artery disease, as indicated by angiography. Surgery confirmed a postinfarction ventricular septal defect and an exsanguinating pseudoaneurysm, highly circumscribed and well apart from the septal defect, involving the anterior wall of the left ventricle. The patient made good recovery following resection of the aneurysm, repair of the septal defect, and placement of 2 bypass grafts.
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