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[Study on the afficacy of hepatitis B immunization among youngsters in Beijing]
Xiao-hong Gong1, Yang-hua Li, Li-rong Liu
1Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Objective:
To evaluating the epidemiological effect after hepatitis B immunization among youngsters in Beijing.
Methods:
A multistage sampling method was used for data collection from immunization cards, reports on field epidemiological survey on hepatitis B virus (HBV) immunization of youngsters and the analysis of infectious diseases. HBsAg, anti-HBs and anti-HBc levels were detected by solid phase radioimmunoassays (SPRIA).
Results:
The average incidence rates of hepatitis B in 10 - 19 years-olds prior to HBV immunization was 12.11-16.89/100 000, while declined to 1.78-10.95/100 000 (chi(2) = 10.71 - 60.45, P < 0.01). HBsAg carrying rate of the youngsters decreased from 6.34% to 1.37% (80.00%) after vaccination (chi(2) = 14.16, P < 0.01).
Conclusion:
Hepatitis B vaccination among youngsters is an effective measure for the prevention and control of hepatitis B virus infection.
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