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Antioxidant and nitric oxide synthase activation properties of Auricularia auricula
Krishnendu Acharya1, Krishnendu Samui, Manjula Rai
1Biotechnology Research Laboratory, Post Graduate Department of Botany, Darjeeling Government College, Darjeeling 734 101, India. krishnendua@rediffmail.com
Abstract:
In vitro evaluation of antioxidant activities of Auricularia auricula showed significant inhibition of lipid peroxidation, and potent hydroxyl radical scavenging activity when compared with standard drug catechin. IC5o value of crude, boiled and ethanolic extracts of A. auricula represented 403, 510, and 373 microg/ml respectively in case of hydroxyl radical scavenging activity and 310, 572 and 398 microg/ml respectively in case of lipid peroxidation. Furthermore, crude, boiled and ethanolic extracts also increase significantly nitric oxide production (664, 191 and 850 pmole/mg dry wt/hr respectively) over the control. The present results revealed that A. auricula had potential therapeutic use.
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