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Reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression

I C Vossinakis1, P Stavroulaki, I Paleochorlidis

  • 1Orthopaedic Department, Achillopoulion Volos General Hospital, Polymeri Street, Volos, Greece. vossinakis@panafoent.gr

Journal of Hand Surgery (Edinburgh, Scotland)
|July 6, 2004
PubMed

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The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
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One of the advantages of...