Chondrosarcoma of the sphenoid sinus resected by an endoscopic approach

Chondrosarcoma of the sinonasal tract is a rare neoplasm. Surgical excision is usually sufficient for low-grade lesions, whereas combined treatment is usually recommended for high-grade lesions. The oncologic outcome depends on a complete resection as well as the grade of the tumor. We present the case of a 35-year-old man presenting with an incidental finding of a chondrosarcoma of the posterior septum and rostrum of the sphenoid sinus. The tumor was completely resected using a transnasal endoscopic approach obtaining negative margins. Surgery is the mainstay treatment for low-grade chondrosarcomas. In selected patients, complete resection can be achieved using transnasal endoscopic approaches.