Related Experiment Video
Updated: Jul 12, 2026

Selection of Plasmodium falciparum Parasites for Cytoadhesion to Human Brain Endothelial Cells
Published on: January 3, 2012
Intravascular schistosomes and complement
1Department of Biomedical Sciences, Division of Infectious Diseases, Tufts University School of Veterinary Medicine, 200 Westboro Road, Grafton, MA 01536, USA. Patrick.Skelly@Tufts.edu
Abstract:
Schistosomes are exposed to a variety of immunological effectors, such as host complement, in the bloodstream of their definitive hosts. The parasites are reported to possess a plethora of regulatory proteins, including molecules acquired from the host, which impede the complement cascade. Evidence for the presence of a surface C2-binding protein, a C3-binding protein and a C8- and C9-binding protein has been reported. In addition, a surface Fc receptor might bind immunoglobulin and limit its ability to fix complement. However, the actual protective role of these proteins in vivo remains unresolved.
More Related Videos
Related Concept Videos
Symbiosis
Complement System
Venous Thrombosis I: Introduction
Diversity of Protists II
Malaria
Amebiasis

