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Updated: Aug 23, 2026

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability
Published on: April 28, 2022
[Is there a link between the food-cobalamin malabsorption and the pernicious anemia?]
E Andrès1, E Noel, N Henoun Loukili
1Service de médecine interne, hôpitaux universitaires de Strasbourg, 1 porte de l'Hôpital, 67091 Strasbourg Cedex, France. emmanuel.andres@chru-strasbourg.fr
Background:
A relation between food-cobalamin malabsorption and pernicious anemia has been suggested, particularly in the event of food-cobalamin malabsorption related to hypochlorhydric atrophic gastritis.
Study Design:
This work describes three cases of well-documented cobalamin deficiency related to food-cobalamin malabsorption in three women aged 56, 82 and 68 Years who had atrophic gastritis (not associated with Helicobacter pylori infection) and later developed authentic pernicious anemia.
Conclusions:
This work illustrates the potential relation between these two disorders responsible for cobalamin deficiency.
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