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Relationship between platelet count and bleeding risk in thrombocytopenic patients
1Puget Sound Blood Center, University of Washington School of Medicine, Seattle 98104-01256, USA. sjslichter@psbc.org
Transfusion Medicine Reviews
|July 13, 2004
Abstract:
Platelets are lost from circulation by 2 mechanisms: senescence and random loss. Approximately 7.1 x 10(3) platelets/microL/d are postulated to be randomly used in maintaining vascular integrity. Thus, in clinically stable patients, major bleeding is unusual unless the platelet count is