Related Experiment Video
Updated: Aug 8, 2026

Raman and IR Spectroelectrochemical Methods as Tools to Analyze Conjugated Organic Compounds
Published on: October 12, 2018
Raman, SERS and theoretical studies of papaverine hydrochloride and its neutral species
S Cîntă Pînzaru1, N Leopold, I Pavel
1Physics Department, Babe-Bolyai University, Kogãlniceanu 1, RO-3400 Cluj-Napoca, Romania. scinta@phys.ubbcluj.ro
Abstract:
Density functional theory (DFT) calculations and an experimental vibrational characterization of papaverine hydrochloride were performed. The computed structural parameters agree very well with the experimental values of the related crystal structure. The pH dependent Raman and SERS spectra of papaverine hydrochloride were recorded and discussed with the assistance of our theoretical results (harmonical vibrational wavenumbers, Raman scattering activities, total electron density and Natural Population Analysis of the molecule) and the SERS surface selection rules. Two different adsorption geometries were found for the corresponding evidenced species of papaverine, protonated and neutral, respectively.
More Related Videos
11:04Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
07:36Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
Related Concept Videos
Racemic Mixtures and the Resolution of Enantiomers
Chirality at Nitrogen, Phosphorus, and Sulfur
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Basicity of Heterocyclic Aromatic Amines
Basicity of Aromatic Amines
Raman Spectroscopy: Overview
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...
Analgesia and Pain Management