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Updated: Aug 23, 2026

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Published on: March 17, 2020
Synchronous squamous cell carcinoma of the stomach, the lung and the skin
K Altundag1, S Yalcin, O Ozkaya
1Institute of Oncology, Department of Pathology, Hacettepe School of Medicine, Ankara, Turkey.
Background:
The incidence of multiple primary cancers is reported to be 0.3-4.3%.
Case Report:
A 70-year-old man was admitted to the hospital because of fatigue, weight loss, epigastric pain with melena. A biopsy taken from a tumoral lesion in the gastric corpus revealed squamous cell carcinoma. A nodular lesion was also detected on the nasal columella and biopsy from this lesion also showed squamous cell carcinoma. Computed tomography performed as a part of metastatic work-up revealed a lesion in the left pulmonary lower lobe. Bronchoscopic biopsy from this lesion also demonstrated squamous cell carcinoma.
Results:
We report a case with synchronous squamous cell carcinoma of the lung, skin and stomach and discuss the multiple synchronous occurrence of carcinoma with the same histopathology in different sites with a review of the literature.
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