Related Experiment Video
Updated: Aug 23, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Is fibre supplementation in paediatric sip feeds beneficial?
A Daly1, T Johnson, A MacDonald
1The Birmingham Children's Hospital, Birmingham, UK. anne.daly@bch.nhs.uk
Insights
Paediatric sip feeds containing fibre improved fibre intake and reduced laxative use in children with chronic illness. These fibre-enriched sip feeds are safe and well-tolerated, offering vital nutritional support.
Area of Science:
- Pediatric Nutrition
- Gastroenterology
- Clinical Trials
Background:
- The efficacy of pediatric fiber-containing sip feeds for children aged 1-6 years (8-20 kg) with chronic illnesses has not been previously evaluated.
- Nutritional support is crucial for children with chronic conditions, and the role of fiber in specialized sip feeds requires investigation.
Purpose of the Study:
- To evaluate the efficacy, safety, and tolerance of a pediatric fiber-containing sip feed compared to a fiber-free control sip feed.
- To assess the impact of fiber-enriched sip feeds on nutritional intake, gastrointestinal tolerance, and relevant health markers in pediatric patients.
Main Methods:
- An open, prospective, parallel study involving 60 children (1-6 years) with chronic illness.
- Participants received either a fiber-containing sip feed (2.0 g/100 ml fiber) or a fiber-free control sip feed for 12 weeks.
- Data collected included blood biochemistry, hematology, anthropometry, tolerance, and food intake at baseline and 12 weeks.
Main Results:
- The group receiving the fiber-containing sip feed showed significantly higher fiber intake (P < 0.0001) and decreased laxative usage.
- The sip feed contributed approximately 50% of the total fiber intake in the intervention group.
- No significant differences were observed in sip feed tolerance, anthropometry, nutritional biochemistry, or hematology between the two groups.
Conclusions:
- Pediatric fiber-containing sip feeds are effective in increasing fiber intake and reducing laxative dependence in children with chronic illnesses.
- These specialized sip feeds are safe, well-tolerated, and provide a significant source of fiber for pediatric patients requiring nutritional support.
- Fiber-enriched sip feeds represent a valuable tool for managing nutritional needs and improving gastrointestinal health in vulnerable pediatric populations.
Abstract:
The usefulness of a paediatric fibre containing sip feeds specifically formulated for paediatrics has not been evaluated. In an open, prospective, parallel study the efficacy, safety and tolerance of a paediatric fibre-containing sip feed designed for children weighing 8-20 kg (1-6 years) was compared with a fibre-free sip feed in 60 children with chronic illness. The subjects either received a trial sip feed containing 150 kcal (100 ml)(-1) and 2.0 g (100 ml)(-1) of fibre or a fibre-free equivalent control sip feed for 12 weeks. Blood biochemistry, haematology, anthropometry, tolerance and food intake data were estimated during week 1 and 12. The fibre intake was higher (P < 0.0001) and laxative usage decreased in the fibre-containing sip feed group. The sip feed provided almost 50% of fibre intake in the trial group. There were no differences in sip feed tolerance, anthropometry, nutritional biochemistry or haematology between the two groups. Sip feeds provide an important source of fibre for sick children with normal gut function requiring nutritional support.
Related Concept Videos
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
Drugs for Treatment of Constipation-Predominant IBS
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
