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Relation between age, ventricular arrhythmia, left ventricular hypertrophy and QT dispersion in patients with

Abdullah M Saadeh1

  • 1Department of Cardiology and Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan. Abdullah_Saadeh@yahoo.com

Acta Cardiologica
|July 17, 2004
PubMed

Insights

Essential hypertension significantly increases risks for left ventricular hypertrophy (LVH), left ventricular mass (LVM), and arrhythmia scores compared to healthy individuals. Age impacts these conditions differently in hypertensive versus healthy subjects.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Geriatric Medicine

Background:

  • Essential hypertension is a prevalent condition associated with cardiovascular complications.
  • Left ventricular hypertrophy (LVH) and left ventricular mass (LVM) are key indicators of cardiac strain.
  • Arrhythmia, assessed by Lown score and QTc dispersion, is a known complication of cardiovascular disease.

Purpose of the Study:

  • To investigate the influence of age on LVH, LVM, QTc dispersion, and Lown score in essential hypertension.
  • To compare these parameters between hypertensive patients and age-matched healthy controls.
  • To identify age-related differences in cardiovascular markers within hypertensive and control groups.

Main Methods:

  • Cross-sectional study comparing 115 hypertensive patients with 41 healthy controls.
  • Assessment of left ventricular hypertrophy (LVH) and left ventricular mass (LVM) using echocardiography or other imaging modalities.
  • Evaluation of QTc dispersion and Lown score for arrhythmia risk stratification.

Main Results:

  • Hypertensive patients exhibited significantly higher Lown scores, LVH, and LVM prevalence than controls.
  • Males, both hypertensive and control, showed higher LVH and LVM than females.
  • LVH and LVM were more common in younger hypertensives, but older in healthy controls. QTc dispersion was higher in hypertensives and older controls, but not older hypertensives.

Conclusions:

  • Essential hypertension is linked to increased LVH, LVM, and arrhythmia risk, irrespective of age.
  • Age-related patterns of LVH and LVM differ between hypertensive patients and healthy individuals.
  • QTc dispersion patterns vary with age and disease status, suggesting complex cardiovascular adaptations.

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