Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Iodine metabolism in postpartum thyroiditis.

S Othman1, D I Phillips, J H Lazarus

  • 1Department of Medicine, University of Wales College of Medicine, Heath Park, Cardiff.

Thyroid : Official Journal of the American Thyroid Association
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A standardised approach to the pathological dissection and reporting of pelvic exenteration specimens: Recommendations from the UK Pelvic Exenteration Network (UKPEN).

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2026
Same author

Matching dynamically varying forces with multi-motor-unit muscle models: a simulation study.

Royal Society open science·2025
Same author

Genetic diversity and population structure of a rare flowering tree endemic to Appalachia, <i>Stewartia ovata</i>.

Ecology and evolution·2024
Same author

Author Correction: Large language models and agricultural extension services.

Nature food·2023
Same author

Large language models and agricultural extension services.

Nature food·2023
Same author

Impact of the COVID-19 pandemic on a post-mortem CT service for adult non-suspicious death.

Clinical radiology·2023

Iodine intake does not appear to cause postpartum thyroiditis (PPT). However, increased urinary iodine excretion in PPT is linked to thyroid destruction, particularly during the hyperthyroid phase.

Area of Science:

  • Endocrinology
  • Immunology
  • Reproductive Health

Background:

  • Postpartum thyroiditis (PPT) is an autoimmune thyroid disorder affecting women after childbirth.
  • The role of iodine intake in the etiology and progression of PPT remains unclear.
  • Thyroid microsomal antibodies are a known risk factor for developing PPT.

Purpose of the Study:

  • To investigate the potential role of iodine intake in the development of postpartum thyroiditis (PPT).
  • To examine the relationship between urinary iodine excretion and thyroid function in women with and without PPT.
  • To understand the dynamics of iodine release during different phases of PPT.

Main Methods:

  • A prospective study involving 1996 pregnant women screened for thyroid antibodies.

Related Experiment Videos

  • Serial measurements of urinary iodine excretion and thyroid function tests over 12 months postpartum.
  • Comparison of antibody-positive women who developed PPT with antibody-negative controls.

    • Main Results:

    • Immediate postpartum urinary iodine excretion did not differ between PPT and control groups.
    • Increased urinary iodine excretion was observed 8-16 weeks postpartum in women with PPT, preceding hypothyroidism.
    • The rise in urinary iodine excretion correlated with decreased serum free thyroxine levels in PPT patients.

    Conclusions:

    • Iodine intake is unlikely to influence the prevalence of postpartum thyroiditis.
    • Increased urinary iodine excretion in PPT reflects intrathyroidal iodine release due to thyroid destruction.
    • This iodine release occurs during the hyperthyroid phase and precedes hormonal changes in hypothyroid PPT.