Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Leukocytoclastic vasculitis].

C Sunderkötter1, J Roth, G Bonsmann

  • 1Universitätsklinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum Ulm, Ulm. cord.sunderkoetter@medizin.uni-ulm.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|July 17, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dermatologie (Heidelberg, Germany)·2025
Same author

Dermatologie (Heidelberg, Germany)·2025
Same author

Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: Localized scleroderma, systemic sclerosis and overlap syndromes.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

[Progressive sclerodactyly in a Gambian farmer].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2021
Same author

[59-year-old male with erythema, edema on the lower leg : Preparation for the specialist examination: part 56].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2019
Same author

Schwere Candida-Balanoposthitis unter gleichzeitiger Therapie mit Secukinumab und dem Antidiabetikum Empagliflozin (Natrium-Glukose-Cotransporter 2 - SGLT2-Inhibitor).

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2019
Same journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral infections of the skin].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral exanthems in children].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Erratum to: Digital health applications and data protection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Virus-induced exanthems in returning travellers].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Venous ulcus cruris-Surgical treatment].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
See all related articles

Leukocytoclastic vasculitis (LcV) is common, often caused by immune complexes. Diagnosis guides treatment, ranging from symptomatic care to immunosuppression for severe cases.

Area of Science:

  • Immunology
  • Dermatology
  • Rheumatology

Background:

  • Leukocytoclastic vasculitis (LcV) is the most frequent type of cutaneous vasculitis.
  • Immune complex deposition in vessel walls commonly triggers LcV.
  • IgA-driven complexes suggest systemic involvement (Henoch-Schönlein purpura), particularly in adults.

Purpose of the Study:

  • To outline the diagnostic approach for LcV.
  • To differentiate LcV subtypes based on immune complex composition and systemic involvement.
  • To guide therapeutic strategies according to LcV severity and etiology.

Main Methods:

  • Review of LcV pathophysiology, clinical presentations, and diagnostic workup.
  • Classification of LcV based on immunoglobulin types (IgA, IgG, IgM) and associated conditions.

Related Experiment Videos

  • Analysis of treatment modalities for uncomplicated, severe, and chronic recurrent LcV.

    • Main Results:

    • LcV can be limited to the skin or indicate systemic disease, including ANCA-associated vasculitis or bacteremia.
    • Diagnostic procedures aim to identify vasculitis type, systemic spread, and underlying causes.
    • Treatment varies from symptomatic relief and corticosteroids to dapsone, colchicine, or immunosuppressants.

    Conclusions:

    • Accurate diagnosis of LcV subtype and systemic involvement is crucial for effective management.
    • Treatment selection for LcV depends on identified causes, severity, and specific clinical features.
    • Prompt and appropriate therapy can mitigate complications and improve outcomes in LcV patients.