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[Dementia with Lewy bodies. A description of a case with a genetic variant]

L Gámez-Morales¹, A M Hernández-Escalona, R Borroto-Regalado

¹Servicio de Neurología, Instituto Nacional de Neurología y Neurocirugía, La Habana, Cuba. lgamez0903@yahoo.es

Revista De Neurologia

|July 17, 2004

Abstract

Introduction:

Dementia with Lewy bodies represents the third cause of dementia in the clinicopathological series reported to date.

Case Report:

A 79-year-old white female with a 3-year history of symptoms of dementia, Parkinsonism and visual hallucinations; the symptoms were difficult to control with medication and there was a family history of similar clinical pictures of dementia in the paternal grandfather, an aunt on the father's side and six siblings. A genetic study was not possible. The study thus involves a patient with relatives that may have had the pure or mixed variant of these dementias, without the DNA study for determining the e4 allele of the gene for apolipoprotein E that has been found most frequently in dementia due to Alzheimer.

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