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Induction of Graft-versus-host Disease and In Vivo T Cell Monitoring Using an MHC-matched Murine Model
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Graft-versus-leukemia effect of allogeneic stem cell transplantation; a Japanese single center study

Ken Ishiyama, Akiyoshi Takami, Shintaro Shiobara

    Haematologica
    |July 20, 2004
    PubMed

    To clarify graft-versus-leukemia effect of graft-versus-host disease, we studied 166 patients treated with allogeneic stem cell transplantation for hematologic malignancies. The cumulative incidence of relapse in patients with acute GVHD was significantly lower than that in patients without acute GVHD, but there was no similar GVL effect for chronic GVHD.

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