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Updated: Aug 23, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
Published on: February 8, 2022
Computed tomography contrast enhancement principles and the use of high-concentration contrast media
1Department of Diagnostic Radiology, Yale New Haven Hospital, New Haven, CT 06906, USA. deusnyc@hotmail.com
Abstract:
Numerous pharmacokinetic and physiologic interactions are involved in the utilization of iodinated contrast in computed tomography. Patient related factors, injection related variables including contrast material concentration, and intravascular and organ specific imaging techniques are but a few of the principles that must be understood. With the advancement of faster CT scanners, these factors must be considered for optimal contrast enhancement.
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