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Psoriatic arthritis.

C P Rajendran1, S G Ledge, Kanaka P Rani

  • 1Department of Rheumatology, Madras Medical College and Government General Hospital, Chennai, Tamil Nadu, India.

The Journal of the Association of Physicians of India
|July 21, 2004
PubMed
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This study on psoriatic arthritis (PsA) in South India found it more prevalent in males, with symmetric polyarthritis being the most common subtype. Arthritis often follows skin lesions, with psoriasis vulgaris being the most frequent skin manifestation.

Area of Science:

  • Rheumatology
  • Dermatology
  • Clinical Medicine

Background:

  • Psoriatic arthritis (PsA) is a chronic inflammatory disease affecting joints and skin.
  • Understanding the clinical patterns of PsA is crucial for effective management.
  • Tertiary referral centers provide valuable insights into disease presentation in specific populations.

Purpose of the Study:

  • To characterize the clinical presentation of psoriatic arthritis (PsA) in a South Indian tertiary care setting.
  • To identify demographic, clinical, and radiographic features of PsA.
  • To compare findings with existing literature on PsA.

Main Methods:

  • Retrospective analysis of case records of 116 patients diagnosed with psoriatic arthritis (PsA).
  • Data collected included demographic, clinical, laboratory, and radiographic variables.

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  • Comparison of collected data with findings from other international studies on PsA.

    • Main Results:

    • PsA predominantly affected males (2:1 ratio) with peak incidence in the fourth and fifth decades.
    • Symmetric polyarthritis was the most common subtype (48.3%), and arthritis typically followed skin lesions (50.8%).
    • Psoriasis vulgaris (81%) was the most common skin lesion, with the scalp being the most frequent hidden site (57.8%).

    Conclusions:

    • Psoriatic arthritis (PsA) exhibits a male predominance and commonly presents as symmetric polyarthritis.
    • The onset of arthritis often occurs after the appearance of skin lesions, primarily psoriasis vulgaris.
    • Elevated inflammatory markers like ESR and CRP are not consistently observed in all PsA patients.