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Sepsis associated with Norwegian scabies in patients with acquired immunodeficiency syndrome

S M Skinner1, R L DeVillez

  • 1University of Texas Health Science Center, San Antonio 78284-7876.

Cutis
|September 1, 1992
PubMed

Insights

Patients with acquired immunodeficiency syndrome (AIDS) and Norwegian scabies face a high risk of sepsis. Bacterial entry through skin fissures in severe scabies can lead to life-threatening infections, warranting prompt antibiotic treatment.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Immunology

Background:

  • Acquired immunodeficiency syndrome (AIDS) compromises immune function, increasing susceptibility to opportunistic infections.
  • Norwegian scabies, a severe form of scabium infestation, presents unique challenges in immunocompromised patients.

Observation:

  • A literature review identified eight cases of Norwegian scabies in AIDS patients, with three complicated by sepsis.
  • A case report details a patient with AIDS and Norwegian scabies who developed Pseudomonas aeruginosa sepsis.

Findings:

  • Severe Norwegian scabies, characterized by extensive skin fissures, creates potential entry points for bacterial pathogens.
  • These fissures significantly elevate the risk of sepsis in patients with both AIDS and Norwegian scabies.

Implications:

  • Empiric antibiotic therapy is recommended for AIDS patients presenting with Norwegian scabies to prevent sepsis.
  • Antibiotic selection should be guided by local bacterial resistance patterns and common pathogens, such as Pseudomonas aeruginosa.

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