Vaginal and cervical atresia in a cynomolgus macaque

A female cynomolgus monkey presented clinically with a caudal abdominal mass noted on a prestudy physical examination. No other clinical abnormalities were noted. An ultrasound examination revealed a mass approximately 2 cm in diameter, which contained fluid with a granular "free-floating" appearance. Within a month the mass enlarged and was visible from external examination. Exploratory laparotomy revealed a mass encompassing the uterus, both ovaries, bladder, and rectum. The animal was euthanized under anesthesia, and the mass was removed, examined, and submitted for histopathology. A diagnosis of vaginal and cervical atresia was made. To the author's knowledge, this is the first description of vaginal and cervical atresia in a laboratory nonhuman primate.