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Updated: Aug 23, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Nutrition and pregnancy: the link between dietary intake and diabetes
1Sansum Diabetes Research Institute, 2219 Bath Street, Santa Barbara, CA 93105, USA. ljovanovic@sansum.org
Abstract:
Pregnancy is a time when serial metabolic changes in the mother are carefully regulated to provide optimum substrate to both mother and fetus. Subtle perturbations in maternal metabolism can have implications not only for the index pregnancy, but also for future generations. The literature provides evidence that maternal nutrition plays a major role in the destiny of the offspring. Both maternal malnutrition and overnutrition are associated with subsequent diabetes in the offspring. Pregnancy represents a window of opportunity for health care providers to change dietary patterns toward habits that will be healthier for the individual now, as well as impacting on the future. The challenge for clinicians is to provide nutritional information based on scientific evidence that facilitates the normalization of fetal nutrition, and thus minimize the risk that the child will develop diabetes.
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