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Updated: Aug 23, 2026

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
Published on: May 27, 2021
Molecular exchange through vesicle membranes: a pulsed field gradient nuclear magnetic resonance study
Anja Rumplecker1, Stephan Förster, Manfred Zähres
1Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim, Germany.
Abstract:
The permeability of block copolymer vesicles is studied using pulsed field gradient nuclear magnetic resonance spectroscopy together with a numerical data analysis procedure. Polyethylene oxide molecules of various molecular masses are used to sample the permeability of the vesicle membrane by observing the trans-membrane exchange process under equilibrium conditions. For shorter polyethylene oxide chains, the analysis yields a nearly linear dependence of the logarithmic trans-membrane exchange rate on the hydrodynamic radius of the sample molecules.
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