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Signal transduction enzymes of vertebrate photoreceptors
1Howard Hughes Medical Institute, University of Washington, Seattle 98195.
Journal of Bioenergetics and Biomembranes
|April 1, 1992
Abstract:
A flash of light initiates a cascade of biochemical reactions inside vertebrate photoreceptor cells, culminating in hydrolysis of intracellular cyclic GMP and hyperpolarization of the cell. The cell recovers by shutting down this cascade and resynthesizing cGMP. Many of the reactions responsible for the excitation and recovery phases of the photoresponse have been identified. Here I review some characteristics of the proteins that participate in these reactions.