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Acute hemorrhagic conjunctivitis outbreak caused by Coxsackievirus A24--Puerto Rico, 2003
Insights
A 2003 outbreak of acute hemorrhagic conjunctivitis (AHC) in Puerto Rico affected nearly half a million people. School-aged children in crowded areas were most at risk, highlighting the need for targeted prevention.
Area of Science:
- Ophthalmology
- Public Health
- Epidemiology
Background:
- Acute hemorrhagic conjunctivitis (AHC) is a contagious eye infection causing sudden redness, swelling, and tearing.
- AHC epidemics have primarily affected the Caribbean since 1981.
- A significant AHC outbreak occurred in Puerto Rico during August-October 2003.
Purpose of the Study:
- To investigate the 2003 AHC epidemic in Puerto Rico.
- To identify the causative agent and risk factors associated with the outbreak.
- To inform public health strategies for AHC prevention and control.
Main Methods:
- Outbreak investigation conducted by the Puerto Rico Department of Health.
- Documentation of illness and physician-reported cases.
- Laboratory confirmation of Coxsackievirus A24 (CA24) as the causative agent.
Main Results:
- An estimated 490,000 individuals experienced illness during the epidemic.
- Over 51,000 cases were reported by healthcare professionals.
- School-aged children (5-18 years) and individuals in crowded urban settings were identified as high-risk groups.
Conclusions:
- Coxsackievirus A24 (CA24) was confirmed as the cause of the 2003 AHC epidemic.
- Targeted prevention strategies, including hygiene education for high-risk populations, are crucial for controlling AHC.
- Rapid information dissemination upon initial AHC detection is vital for outbreak management.
Abstract:
Acute hemorrhagic conjunctivitis (AHC) is an epidemic form of highly contagious conjunctivitis and is characterized by sudden onset of painful, swollen, red eyes, with conjunctival hemorrhaging and excessive tearing. Since 1981, when AHC was first detected in the Western Hemisphere, three major epidemics had occurred until 2003, all affecting the Caribbean. During August-October 2003, a fourth epidemic occurred in Puerto Rico (2000 population: 3.8 million). This report summarizes the outbreak investigation conducted by the Puerto Rico Department of Health (PRDOH), which documented an estimated 490,000 persons with illness, including >51,000 cases reported by physicians; demonstrated laboratory evidence of Coxsackievirus A24 (CA24); and determined that school-aged children (i.e., aged 5-18 years) and those living in crowded urban areas were at highest risk. To control outbreaks of AHC, prevention methods (e.g., frequent hand washing and avoidance of sharing towels and bedding) should be targeted to groups at highest risk, and information should be disseminated after the first report of AHC in the area.
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