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Updated: Aug 23, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
Intraoperative recombinant activated factor VII for emergent epidural hematoma evacuation
Tamas Szabo1, Syed Ali, Enrico M Camporesi
1Department of Anesthesiology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA. tamas.szabo@excite.com
Abstract:
We report a case of a chronically anticoagulated 59-yr-old woman who underwent an L4 to L5 epidural block to relieve her low back pain and subsequently developed a T7 to L5 epidural hematoma with cauda equina and conus compression. Fresh frozen plasma and vitamin K were given before surgery, whereas recombinant activated factor VII was administered during surgery to reverse the coagulopathy and to enable the emergent laminectomy and hematoma evacuation. Recombinant activated factor VII administration proved to be a useful adjunct in the emergent surgical management of a thoracolumbar epidural hematoma.
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