Related Experiment Video
Updated: Aug 23, 2026

The α-test: Rapid Cell-free CD4 Enumeration Using Whole Saliva
Published on: May 16, 2012
Salivary gland disease in pediatric HIV patients: an update
Andres Pinto1, Scott S De Rossi
1Department of Oral Medicine, University of Pennysylvania, Philadelphia, Penn, USA. apinto@dolphin.upenn.edu
Abstract:
Oral manifestations are one of the earliest clinical indicators of HIV infection and progression in children. Prompt recognition of these signs and symptoms by dental providers can help in the diagnosis and intervention of delaying the progression of HIV disease to AIDS. Salivary gland disease is a common manifestation of HIV infection in pediatric patients, presenting either as gland enlargement and/or xerostomia. The parotid glands by far are most frequently affected, though the other major glands are commonly involved. Diseases of the salivary glands and the corresponding quantitative changes in saliva affect the homeostasis of the oral cavity and account for significant morbidity during the progression of HIV disease. This paper summarizes the research on HIV-related salivary gland disease and outlines treatment and management considerations.
Related Concept Videos
Herpes
Respiratory Syncytial Virus Disease
Cryptococcal Meningitis
Poliomyelitis
Retrovirus Life Cycles
Genital Herpes

