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Updated: Aug 19, 2026
Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis
Published on: May 6, 2021
Relationship between changes in rat behavior and integral biochemical indexes determined by laser correlation
G A Romanova1, F M Shakova, O I Kovaleva
1Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia.
Abstract:
Experiments on rats showed that Noopept improved retention and retrieval of conditioned passive avoidance response after phototrombosis of the prefrontal cortex (a procedure impairing retention of memory traces). The impairment of mnesic functions was accompanied by changes in integral biochemical indexes of the plasma determined by laser correlation spectroscopy. Treatment of behavioral disorders with Noopepet normalized biochemical indexes.
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