Related Experiment Video
Updated: Aug 23, 2026

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
Published on: August 9, 2016
Serrated adenomas of the cardia
1Gastrointestinal and Liver Pathology Research Laboratory, Department of Pathology, Karolinska Institute and Hospital, 171 76 Stockholm, Sweden. Carlos.Rubio@onkpat.ki.se
Abstract:
Adenomas of the stomach are histologically classified into tubular and villous adenomas, mixed (tubulovillous) and papillary phenotypes being also recognized. They are localized in the antrum and the body. In a previous work we reported a case of serrated adenoma of the cardia having, at the time of diagnosis, an invasive growth. In this communication we report five newly identified cases of serrated adenomas of the cardia. The five neoplasias were characterized by serrated indentations furnished with dysplastic epithelium. Five out of six serrated adenomas--including the previously reported case--had, in addition, an invasive or a suspected invasive carcinoma. The latter case had at the time of diagnosis lung and liver metastasis. Metastases were also demonstrated in two additional cases. In similarity with other adenoma phenotypes, serrated adenomas of the cardia have a propensity to evolve into invasive carcinoma, a phenomenon that appears to be size-dependent.
Related Concept Videos
Esophageal Achalasia
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Pyloric Obstruction
Peptic Ulcer