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Possible subdural hematoma associated with Ginkgo biloba
Lucinda G Miller1, Barton Freeman
1Miller Pharmacotherapy Consultants, Inc., 3531 Beau Brummel, Amarillo, TX 79121, USA. lucinda.miller.rx@worldnet.att.net
Journal of Herbal Pharmacotherapy
|July 28, 2004
Summary
Ginkgo biloba may increase the risk of subdural hematoma, especially in older adults. This case report highlights a potential adverse effect of this popular herbal supplement.
Area of Science:
- Neurology
- Pharmacology
- Geriatrics
Background:
- Subdural hematomas can occur after head trauma.
- Ginkgo biloba is widely used for cognitive enhancement.
- Ginkgo biloba contains ginkgolide B, a platelet activating factor inhibitor.
Purpose of the Study:
- To report a case of subdural hematoma potentially linked to Ginkgo biloba use.
- To raise awareness about the potential risks of Ginkgo biloba.
Main Methods:
- Case report of a 78-year-old male patient.
- Clinical presentation, diagnostic imaging (CAT scan), and surgical findings.
- Review of patient's medication history, including Ginkgo biloba.
Main Results:
- Patient presented with symptoms of subdural hematoma after a fall.
- A large chronic subdural hematoma was surgically evacuated.
- Patient was taking Ginkgo biloba and lisinopril prior to symptom onset.
Conclusions:
- Ginkgo biloba, due to ginkgolide B, may increase the risk of subdural hematoma.
- This association warrants further investigation given the widespread use of Ginkgo biloba.
- Caution and monitoring may be needed for individuals taking Ginkgo biloba, especially those with risk factors for bleeding.