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[Ectopic thyroid: two cases].

L Cherif1, Y Lakhoua, K Khiari

  • 1Service de médecine interne A, hôpital Charles Nicolle, Boulevard 9 Avril 1006 BS Tunis, Tunisie. cheriflotfi@yahoo.com

Annales D'Endocrinologie
|July 28, 2004
PubMed
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Ectopic thyroid, a rare cause of hypothyroidism, can occur in the sublingual area. Diagnosis relies on imaging, and treatment involves L-thyroxine hormone replacement therapy.

Area of Science:

  • Endocrinology
  • Rare Diseases
  • Medical Imaging

Background:

  • Ectopic thyroid is a rare condition, affecting 1 in 4000 to 8000 patients with hypothyroidism.
  • The precise etiological and pathogenic mechanisms underlying ectopic thyroid remain largely unknown.
  • Diagnosis is typically confirmed through characteristic imaging findings.

Observation:

  • This report details two adult female cases of hypothyroidism associated with ectopic sublingual thyroid glands.
  • One patient was diagnosed with hypothyroidism at 13 and ectopic thyroid 7 years later.
  • Physical examination revealed a palpable thyroid gland in both patients, with a sublingual gland noted in the first.

Findings:

  • Thyroid scintigraphy confirmed ectopic thyroid in both cases.

Related Experiment Videos

  • Computed tomography (CT) and magnetic resonance imaging (MRI) supported the diagnosis in the second patient.
  • Both patients received successful hormonal substitution therapy with L-thyroxine.

    • Implications:

    • This case report contributes to understanding the clinical presentation and diagnostic approaches for ectopic thyroid.
    • It underscores the importance of considering ectopic thyroid in patients with hypothyroidism, especially when the gland is palpable.
    • Further research into the genetic and developmental factors may elucidate the pathogenesis of ectopic thyroid.