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Updated: Aug 23, 2026

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
Published on: June 26, 2020
Two dimensional PNA/DNA arrays: estimating the helicity of unusual nucleic acid polymers
Philip S Lukeman1, Alexander C Mittal, Nadrian C Seeman
1NYU Department of Chemistry, 31 Washington Place, New York, NY 10003, USA.
Abstract:
We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.
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