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Multi-use Venturi nasal atomizer contamination in a clinical rhinologic practice
Marc G Dubin1, David R White, Christopher T Melroy
1Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
American Journal of Rhinology
|July 31, 2004
Summary
Nasal atomizers can become contaminated with microbes. Wiping these devices with isopropyl alcohol effectively prevents microbial growth for up to two weeks, reducing contamination risks.
Area of Science:
- Microbiology
- Pharmaceutical Science
- Medical Device Sterilization
Background:
- Cross-contamination in Venturi atomizers is a known issue.
- Nasal atomizers may harbor microbial contamination, raising clinical concerns.
Purpose of the Study:
- To assess microbial contamination in Venturi nasal atomizers.
- To evaluate the efficacy of isopropyl alcohol wiping in reducing contamination.
Main Methods:
- Atomizers were filled with lidocaine or Tyzine and tested for contamination over 28 days.
- Cultures were taken from the atomizer contents, nozzle, lumen, and solution.
- Phase II involved wiping atomizers with isopropyl alcohol between uses.
Main Results:
- Initial contamination was observed in 12 lidocaine and 3 Tyzine bottles.
- Lidocaine bottles showed significantly higher contamination at 2 weeks (p=0.02).
- Isopropyl alcohol wiping significantly reduced lidocaine bottle contamination at 2 weeks (p=0.02).
Conclusions:
- Nasal atomizers may experience microbial contamination of uncertain clinical importance.
- Wiping atomizers with isopropyl alcohol effectively eliminates microbial growth for a 2-week period.