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Experience with granulocytapheresis in Crohn's disease
F Cuenca1, J García Paredes, J L Mendoza
1Service of Digestive Diseases, IBD Unit, Hospital Clínico San Carlos. Madrid, Spain. cuencaalarcon@yahoo.com
Revista Espanola De Enfermedades Digestivas
|July 31, 2004
Abstract
Objective:
To describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique.
Conclusions:
Granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish "optimal patient" selection, re-treatment interval, and number of sessions.