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Studies on serum triglyceride level in patients with myocardial infarction
M S Hafiz1, M I Arslan, S Banarjee
1Rajshahi Medical College, Rajshahi, Bangladesh.
Insights
High serum triglyceride levels are significantly elevated in patients experiencing myocardial infarction (MI), a leading cause of premature death. This finding suggests a potential link between elevated triglycerides and MI incidence in Bangladeshi populations.
Area of Science:
- Cardiology
- Biochemistry
- Public Health
Background:
- Myocardial Infarction (MI) is a primary cause of mortality globally, with rapidly increasing incidence in developing nations.
- Elevated serum triglyceride concentrations are implicated as a modifiable risk factor for cardiac events, including MI.
- Understanding triglyceride levels in specific populations, such as in Bangladesh, is crucial for preventative strategies.
Purpose of the Study:
- To determine serum triglyceride levels in healthy Bangladeshi subjects.
- To compare serum triglyceride levels between Bangladeshi patients with MI and healthy controls.
- To evaluate the association between serum triglyceride levels and MI in the Bangladeshi population.
Main Methods:
- A comparative study involving 50 subjects (30 controls, 20 MI patients) was conducted.
- Serum triglyceride levels were measured in both control and patient groups.
- Data was collected between July 2001 and December 2002 at BSMMU and NICVD, Dhaka.
Main Results:
- The mean serum triglyceride level in the control group was 117.07 +/- 32.41 mg/dL.
- The mean serum triglyceride level in the MI patient group was significantly higher at 176.87 +/- 37.15 mg/dL.
- A statistically significant difference in serum triglyceride levels was observed between MI patients and healthy controls.
Conclusions:
- The study indicates a significant elevation of serum triglyceride levels in Bangladeshi patients diagnosed with Myocardial Infarction.
- While definitive conclusions require further investigation, high serum triglyceride concentration is suggested as a contributing factor to MI incidence.
- These findings underscore the importance of managing triglyceride levels for cardiovascular health in Bangladesh.
Abstract:
Myocardial Infarction (MI) is the most common form of heart disease and the single most important cause of premature death in the developed and developing world. Unfortunately the incidence of the condition is increasing rapidly in many developing countries like Bangladesh. Effort should therefore be taken to minimize the risk factors of MI. Large scale randomized clinical trials have shown that lowering high triglyceride concentration mainly by drugs reduces the risk of cardiac events like MI. So the present work has been designed to see the serum triglyceride levels in normal healthy subjects, to compare serum triglyceride levels in patients with MI and those of healthy subjects and to evaluate the association of serum triglyceride in Bangladeshi MI patients. The present study was carried out in the Department of Biochemistry, BSMMU in collaboration with Department of Cardiology, BSMMU and NICVD, Dhaka during the period of July 2001 to December 2002. A total of 50 subjects were selected, Group A (30 subjects of control ) and Group B (20 subjects of test ). The mean level of serum triglyceride in control subjects were 117.07 +/- 32.41 mg/d1 and in test subjects were 176.87 +/- 37.15 mg/d1. So the present study showed that serum triglyceride level is significantly higher in patients with MI. From the present study, it is difficult to draw any definite conclusion but suggested that high serum triglyceride concentration is a cause of the incidence of MI.
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