Varicella zoster virus meningitis in a previously immunized child
1Department of Pediatrics, University of Chicago, Chicago, Illinois, USA. jschwab@peds.bsd.uchicago.edu
Pediatrics
|August 3, 2004
Insights
A previously vaccinated 5-year-old developed varicella-zoster meningitis and temporary hearing loss. Prompt treatment with acyclovir led to a complete recovery, highlighting effective management strategies.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Immunology
Background:
- Varicella-zoster virus (VZV) can cause serious neurological complications, including meningitis.
- Despite varicella immunization, breakthrough infections can occur, necessitating vigilance in pediatric populations.
Observation:
- A previously healthy 5-year-old child, immunized against varicella, presented with symptoms of meningitis.
- The child experienced a transient episode of sensorineural hearing loss during the illness.
Findings:
- Cerebrospinal fluid analysis confirmed VZV meningitis.
- The patient received intravenous acyclovir, demonstrating a positive clinical response.
Implications:
- This case underscores the potential for VZV meningitis even in immunized children.
- Early diagnosis and antiviral treatment are crucial for favorable outcomes, including the prevention of long-term sequelae like hearing impairment.
Abstract:
We are reporting a previously well 5-year-old child with varicella-zoster meningitis who had a history of a previous immunization against varicella. This child also developed a transient sensorineural hearing loss. The child was treated with acyclovir and made a full recovery.
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