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Updated: Aug 23, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Conjunctival keratoacanthoma
Fernanda Braga Perdigão1, Paulo de Tarso P Pierre-Filho, Renato José Mendonça Natalino
1Department of Ophthalmology, State University of Campinas (UNICAMP), Campinas, SP, Brazil. fernandaperdigao@yahoo.com.br
Abstract:
Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctival keratoacanthoma is rare; differential diagnosis of conventional squamous cell carcinoma and keratoacanthoma can be difficult. We recommend complete surgical excision and careful follow-up of crateriform squamous proliferations.
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