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New cytotoxic alkyl phloroglucinols from Protorhus thouvenotii
Shugeng Cao1, Jennifer K Schilling, Armand Randrianasolo
1Department of Chemistry M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Planta Medica
|August 12, 2004
Abstract:
Two new cytotoxic alkylene phloroglucinols and one known compound were isolated through chromatographic separation from the methanolic extract of the dried fruits of Protorhus thouvenotii (Anacardiaceae). The compounds showed marginal in vitro cytotoxicity in the A2780 ovarian cancer cell line assay with an IC50 of 11 microg/mL.
