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PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes

Karine Laulagnier1, David Grand, Arnaud Dujardin

  • 1Département Lipoprotéines et Médiateurs Lipidiques, INSERM U563, CPTP, Bât C, CHU Purpan, Place Baylac, BP3028, 31024 Toulouse Cedex 3, France.

FEBS Letters
|August 12, 2004
PubMed

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Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...