Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Depression and modern neuroimaging].

C Vollmert1, H Tost, S Brassen

  • 1NMR-Forschung und Klinik für Psychiatrie und Psychotherapie, Zentralinstitut für Seelische Gesundheit, Mannheim.

Fortschritte Der Neurologie-Psychiatrie
|August 12, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations of preterm birth and neonatal stress exposure with chronic pain in adulthood - Results from the Gutenberg prematurity study.

Journal of psychosomatic research·2024
Same author

Epigenetic signatures in antidepressant treatment response: a methylome-wide association study in the EMC trial.

Translational psychiatry·2022
Same author

[Cohort studies in child and adolescent psychiatry].

Der Nervenarzt·2020
Same author

[Wearables for context-triggered assessment in psychiatry].

Der Nervenarzt·2019
Same author

[Rheumatism and the mind-A mini review].

Der Orthopade·2019
Same author

Effects of BDNF Val<sup>66</sup>Met genotype and schizophrenia familial risk on a neural functional network for cognitive control in humans.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2018

Neuroimaging reveals brain changes in depressive disorders, affecting emotional processing and network interactions. Future research aims to identify subgroups and improve depression therapies.

Area of Science:

  • Neuroscience
  • Psychiatry

Background:

  • Depressive disorders are associated with alterations in brain regions involved in emotional processing.
  • Existing research highlights morphological changes in emotionally relevant brain networks.

Purpose of the Study:

  • To review the current status of neuroimaging research in depressive disorders.
  • To explore functional and morphological brain alterations in depression.
  • To discuss future directions for neuroimaging in understanding and treating affective disorders.

Main Methods:

  • Review of modern neuroimaging techniques including PET, SPECT, MR-Volumetry, functional MRI, and MR-Spectroscopy.
  • Analysis of findings from morphological and functional neuroimaging studies in depressive disorders.
  • Inclusion of specific study findings on emotional cue processing and brain activation patterns.

Related Experiment Videos

Main Results:

  • Depressive disorders show alterations in the basal ganglia, frontal cortex, and limbic system (hippocampus, amygdala).
  • Depressive patients exhibit different activation patterns in the frontal lobe and amygdala during emotional cue processing.
  • Deficits in processing emotional and non-emotional cues were observed in posterior-parietal and prefrontal areas.
  • Affective modulation in healthy subjects involves balanced ventral-limbic and dorsal-neocortical interactions, which are unbalanced in depression.

Conclusions:

  • Modern neuroimaging provides valuable insights into the neurobiology of depressive disorders.
  • Findings suggest distinct neurofunctional patterns associated with depression, particularly in emotional processing.
  • Future neuroimaging research holds promise for identifying neurofunctional subgroups and developing personalized therapies for affective disorders.