Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modeling compositionality by dynamic binding of synfire chains.

Moshe Abeles1, Gaby Hayon, Daniel Lehmann

  • 1Department of Physiology and the Center for Neural Computation, The Hebrew University, Jerusalem, Israel. abeles@vms.huji.ac.il

Journal of Computational Neuroscience
|August 13, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Controlled Nanopore Sizes in Supraparticle Supports for Enhanced Propane Dehydrogenation with GaPt SCALMS Catalysts.

ACS applied nano materials·2024
Same author

Correction to: Comparison of anti-fracture effectiveness of zoledronate, ibandronate and alendronate versus denosumab in a registry-based cohort study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2023
Same author

Comparison of anti-fracture effectiveness of zoledronate, ibandronate and alendronate versus denosumab in a registry-based cohort study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2023
Same author

Incidence of Atypical Femoral Fractures in Patients on Osteoporosis Therapy-A Registry-Based Cohort Study.

JBMR plus·2022
Same author

Risk of Osteonecrosis of the Jaw Under Denosumab Compared to Bisphosphonates in Patients With Osteoporosis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2021
Same author

Sex-Specific Human Cardiomyocyte Gene Regulation in Left Ventricular Pressure Overload.

Mayo Clinic proceedings·2020
Same journal

Hierarchical learning creates invariant schema within plastic neural networks.

Journal of computational neuroscience·2026
Same journal

Intrinsic chaos control in cortical circuits: A minimal E-I-M rate model for primary visual cortex.

Journal of computational neuroscience·2026
Same journal

Modeling developmental spiking behavior driven by ionic current dynamics of mouse and human inner hair cells using a calcium-enhanced Izhikevich framework.

Journal of computational neuroscience·2026
Same journal

A biophysically grounded model of glutamatergic synaptic transmission integrating glutamate transport, receptor kinetics, and electrotonic effects.

Journal of computational neuroscience·2026
Same journal

When can neuronal activity-dependent homeostatic plasticity maintain circuit-level properties?

Journal of computational neuroscience·2026
Same journal

A charge conservative finite volume discretization of the Hodgkin-Huxley model.

Journal of computational neuroscience·2026
See all related articles

This study shows that synfire chains can achieve compositionality, enabling hierarchical mental representations. Synchronization of these chains, regulated by inhibition, solves the part-binding problem and demonstrates priming.

Area of Science:

  • Computational Neuroscience
  • Cognitive Science
  • Neural Networks

Background:

  • Compositionality is crucial for complex cognition, allowing hierarchical mental representations.
  • Existing neural network models face challenges in achieving robust compositionality.
  • Synfire chains are a proposed neural mechanism for information processing.

Purpose of the Study:

  • To investigate the feasibility of synfire chains in manifesting compositionality.
  • To explore how synchronization among synfire chains can support part-whole binding.
  • To evaluate the role of inhibition in regulating synfire chain synchronization.

Main Methods:

  • Detailed computational simulations of synfire chain networks.
  • Numerical analysis of wave propagation dynamics in synfire chains.

Related Experiment Videos

  • Modeling hierarchical systems incorporating synfire chains and inhibitory neurons.

    • Main Results:

    • Synfire chains synchronize waves with specific cross-links, enabling binding.
    • Global inhibition effectively prevents spurious synchronization.
    • Inhibitory neurons enhance the selection of synchronizing synfire chains.
    • Hierarchical synfire chain systems resolve part-binding and exhibit priming.

    Conclusions:

    • Synfire chains offer a viable mechanism for neural compositionality.
    • Synchronization, modulated by inhibition, is key to binding and hierarchical representation.
    • The proposed model aligns with requirements for compositional neural networks.