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Published on: October 23, 2011
Prospective validation of a perinatal bacterial vaginosis screening risk score
Lisa M Pastore1, Tonya S King, Ida J Dawson
1Department of Obstetrics and Gynecology, School of Medicine, University of Virginia, Charlottesville, VA 22908-0712, USA.
Objective:
Prospectively validate an antenatal bacterial vaginosis (BV) risk score at two public health department obstetrics clinics.
Study Design:
Women (n=409) entering prenatal care received a BV risk score (range 0 to 16) at their first visit and at 24 to 28 weeks' gestation. BV was measured with Gram-stained vaginal smears. Normal discharge was used as a surrogate for being asymptomatic.
Results:
Approximately half of the women scored > or =3 at each assessment. In total 29% had true BV at the first assessment (13% at the second assessment). The BV risk score (> or =3) had 91% sensitivity and 63% specificity, and the BV risk score (> or =5) had 88% sensitivity and 76% specificity. Among true cases, 42% were asymptomatic, of which 77% had risk scores > or =3. All symptomatic BV cases had risk scores > or =3.
Conclusion:
In practice, the risk score identified both asymptomatic and symptomatic cases. Asymptomatic women are of particular interest because they are not screened for BV under current practice guidelines.
