Related Experiment Video
Updated: Aug 23, 2026

Mouse Oocyte In Vitro Maturation, Fertilization, and Culture of Preimplantation Embryos
Published on: May 29, 2026
[Experimental study on effect of erzhi tiangui recipe on quality of oocyte in mice]
Fang Lian1, Zheng-gao Sun, Jian-wei Zhang
1The Reproductive and Hereditary Center of the Affiliated Hospital of Shandong University of TCM, Jinan 250011. flian@chinaivf.com
Objective:
To observe the effect of Erzhi Tiangui recipe (ETR) on quality of oocyte in the process of external fertilization and embryo-transplantation.
Methods:
Eighty mice were randomly divided into 4 groups, Group A treated with ETR plus human menopausal gonadotropin (HMG), Group B with ETR, Group C with HMG and Group D with normal saline. Ovulation test and cleavage test were conducted to observe the effect of treatment on quality of oocytes.
Results:
The difference on ovulation number between Group A and C was insignificant, but the difference in comparison between the two groups was significant in aspects of oocyte morphological scoring, fertilization rate and cleavage rate (P<0.05).
Conclusion:
ETR could play its effect synergistically with Western medicine, and raise the quality of oocytes.
