Related Experiment Videos
Effects of diabetes on female voiding behavior
Wei-Chia Lee1, Huey-Peir Wu, Tong-Yuan Tai
1Departments of Urology and Internal Medicine, College of Medicine, National Taiwan University and Taipei Municipal Hoping Hospital, 7 Chungshan South Road, Taipei, Taiwan.
The Journal of Urology
|August 18, 2004
Summary
Women with type 2 diabetes exhibit altered voiding patterns, including nocturia and reduced flow rates. Peripheral neuropathy is a key factor in diabetic urinary dysfunction.
Area of Science:
- Urology
- Endocrinology
- Nephrology
Background:
- Type 2 diabetes mellitus (T2DM) is a systemic disease affecting multiple organs.
- Diabetic complications can impact lower urinary tract function, leading to voiding dysfunction.
- Understanding voiding behavior in diabetic women is crucial for managing their health.
Purpose of the Study:
- To compare voiding behaviors in women with T2DM versus non-diabetic controls.
- To identify factors associated with voiding dysfunction in women with T2DM.
Main Methods:
- A cohort of 194 women with T2DM and 162 non-diabetic controls were evaluated.
- Lower urinary tract symptoms were assessed using a validated questionnaire.
- Free flow analysis and post-void residual urine estimates were performed to determine emptying efficiency.
Main Results:
- Women with T2DM reported significantly higher nocturia, weaker urinary streams, and lower voided volumes and maximal flow rates compared to controls.
- A higher incidence of significant post-void residual urine was observed in women with T2DM.
- Peripheral neuropathy was independently associated with reduced emptying efficiency in diabetic women.
Conclusions:
- T2DM significantly impacts voiding patterns in a substantial proportion of women.
- Peripheral neuropathy is a critical factor contributing to voiding dysfunction in women with diabetes.
- These findings highlight the need for screening and management of urinary symptoms in diabetic women.